This variant is to address the “swingyness” of solitaire and I believe adds to the story logic of all comics...that is, heroes suffer setbacks but always come back to try again.
Solitaire Variant Rules
When you would lose the game, immediately refresh all characters. Heal all damage on all characters. Replenish upgrades etc.
Remove all Threat from Main Scheme and discard all other Encounter cards except Villain and cards attached to Villain, and Nemesis and Nemesis Side Scheme if in play.
Add one Threat to the Main Scheme and add one Expert card to the Encounter deck.
Re-start the game.