I'm starting to think that the best way (if not the only way) we are going to see a Talisman app for I-Pad/Android is for there to be a decent set of rules for a solo game. I have seen a couple of efforts on Board Game Geek (my favourite being the Reaper alternative) that are pretty good, but I think it needs to be better.
I have started to develop some ideas around NPC Adventure Cards & NPC Spell Cards (that may even be able to be sold as a solo play expansion if FFG like them enough) to simulate other players. I also think the Adventure Cards could be split into 3 stacks. Stack one would be for early game play, with the aforementioned NPC Cards shuffled in. Triggers for Stack 2 might be 10 Str or 10 Cr, and Stack 2 would have more NPC cards and a Portal of Power Card thrown in (signifying a countdown of 7 turns until the player begins to suffer the command spell effects). Stack 3 would be for objects that are up for grabs in the event that you defeat a NPC (you would draw 5 cards and if there was an object among the cards you could take it as your prize for winning the combat).
Shouldn't be too hard to program as an app.