The first preview reveals a few things and hints at others:
1) Double spice blows, previously an "Advanced Game" rule, is now the standard. This is interesting. I hope it doesn't mean that Advanced Game's combat rules are being used, as they'd make even less sense in this setting.
2) Emperor gets his optional ability as standard. This could indicate anything. Maybe they thought the Emperor needed more flavor. Maybe everyone is getting their optional rules standard. I hope the other factions have new abilities instead of Avalon Hill's optional abilities, as some were overpowered (Harkonnen) and some were overly complex (Bene Gesserit).
3) There's no alliance ability listed. I had hoped they'd come up with something for Emperor so he wouldn't be the only one without an ability, but this is better than listing an ability like in the original that causes mass confusion as to whether it is an ability at all. It's possible this means no one has an alliance ability, but I highly, highly doubt this.
4) An assumption: If you look at the map, five territories have a red dot and another dot (green?). They are spaced out similar to the strongholds of Dune, so they are likely the strongholds. The green dot probably means an area protected from bombardment, which informs our understanding of the rest of the map.
5) The artwork is super cool.
Can't wait for the next previews, and I'm glad this is still on schedule for first quarter. While the graphic design of the map doesn't appeal to me particularly, the layout seems interesting. I'm thinking there will be more reason to actually move on the map in this game, unlike Dune where, unless you have ornithopters or are the Fremen, you pretty much ship everywhere. Fewer territories (28, I think I counted) means everything is closer together.