This obviously goes with the recent post on the page as well, but am I the only one who is perhaps a bit 'meh' on the Apotheosis thing? I'm not a huge fan of designed 'end points' in games, it can seem great in theory, but almost seems like a very real hurdle in the way of sustained, long term campaigns in Black Crusade.
I'm also a bit sad, as I was hoping Daemon Prince level play was going to be supported, not the 'win' condition!
Also, mutations, while they seem to work well for Fantasy, they always seemed a lot less common amongst the BIG champions of Chaos in 40k, most of the big name Traitor Marines don't seem to have them (Barring of course Plague Marines), and some of the really powerful ones in the books seemed to have full on control of how they end up looking (See for instance the leaders in the last Grey Knights trilogy book - though it seems at least some of them are probably Daemon Princes, maybe?)
To me it's a shame that some of them, especially the more 'icky' ones are probably going to be likely, I really hope it is possible to play a Chaos Follower who is trying to embrace it in such a way that they don't get mutations like mad but can still be powerful.