So after reading Tom's report, and seeing his comment about how "he wasn't that concerned about Agency," it starting me wondering why. It seems to have some of the best answers for monsters and villainous characters, and provide some relatively cheap answers to a few, big, dudes.
An example is Nathaniel Elton, a 3-cost heroic character with willpower that allows you to exhaust a heroic character to exhaust a villainous character, which can help kneel out Glaaki, Nug, or any other bad ancient one (except Y'Glonac). They have pretty cheap heroic characters as well. Another example is Paranormal Specialist, which can bounce a big ancient one. Sure, it has to be day, but there are a couple of support answers for that in Beneath the Burning Sun and The Rays of Dawn (the latter reducing the potency of monsters significantly), and if you're scared of support destruction there is The Daydreamer. Combining these with enough domains seems to create enough of a rush/stall strategy to take on a deck like Yog-Shub at least with a chance of success, no?
Agency is one faction that I've never really explored because they seem to have the most "vanilla" (i.e. straightforward) cards, and I have typically been drawn to the more interesting interactions of Yog and Syndicate. However, the well-rounded character base also seems to be a strength.
Any thoughts about Agency for tournament viability?